achim kramer lab

:journal club



home

research

people

publications

jobs

contact

links

journal club

project seminar

lectures


16.12.2014 : Sebastian
Transcriptional program of Kpna2/Importin-?2 regulates cellular differentiation-coupled circadian clock development in mammalian cells.
Umemura Y, Koike N, Matsumoto T, Yoo SH, Chen Z, Yasuhara N, Takahashi JS, Yagita K.
Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):E5039-48. doi: 10.1073/pnas.1419272111. Epub 2014 Nov 11.

09.12.2014 : AG Westermark
Circadian rhythm. Dysrhythmia in the suprachiasmatic nucleus inhibits memory processing.
Fernandez F, Lu D, Ha P, Costacurta P, Chavez R, Heller HC, Ruby NF.
Science. 2014 Nov 14;346(6211):854-7. doi: 10.1126/science.1259652.

02.12.2014 : Veronika
Specificity in Circadian Clock Feedback from Targeted Reconstitution of the NuRD Corepressor.
Kim JY, Kwak PB, Weitz CJ.
Mol Cell. 2014 Nov 20. pii: S1097-2765(14)00827-2. doi: 10.1016/j.molcel.2014.10.017. [Epub ahead of print]

25.11.2014 : Thomas
A circadian gene expression atlas in mammals: Implications for biology and medicine.
Zhang R, Lahens NF, Ballance HI, Hughes ME, Hogenesch JB.
Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16219-24. doi: 10.1073/pnas.1408886111. Epub 2014 Oct 27.

18.11.2014 : Achim
FGF21 regulates metabolism and circadian behavior by acting on the nervous system.
Bookout AL, de Groot MH, Owen BM, Lee S, Gautron L, Lawrence HL, Ding X, Elmquist JK, Takahashi JS, Mangelsdorf DJ, Kliewer SA.
Nat Med. 2013 Sep;19(9):1147-52. doi: 10.1038/nm.3249. Epub 2013 Aug 11.

11.11.2014 : Silke
Transkingdom control of microbiota diurnal oscillations promotes metabolic homeostasis.
Thaiss CA, Zeevi D, Levy M, Zilberman-Schapira G, Suez J, Tengeler AC, Abramson L, Katz MN, Korem T, Zmora N, Kuperman Y, Biton I, Gilad S, Harmelin A, Shapiro H, Halpern Z, Segal E, Elinav E.
Cell. 2014 Oct 23;159(3):514-29. doi: 10.1016/j.cell.2014.09.048. Epub 2014 Oct 16.

04.11.2014 : Bert
Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock.
Ye R, Selby CP, Chiou YY, Ozkan-Dagliyan I, Gaddameedhi S, Sancar A.
Genes Dev. 2014 Sep 15;28(18):1989-98. doi: 10.1101/gad.249417.114.

28.10.2014 : Neta
The role of the endocrine system in feeding-induced tissue-specific circadian entrainment.
Sato M, Murakami M, Node K, Matsumura R, Akashi M.
Cell Rep. 2014 Jul 24;8(2):393-401. doi: 10.1016/j.celrep.2014.06.015. Epub 2014 Jul 10.

21.10.2014 : Ute
Lhx1 controls terminal differentiation and circadian function of the suprachiasmatic nucleus.
Bedont JL, LeGates TA, Slat EA, Byerly MS, Wang H, Hu J, Rupp AC, Qian J, Wong GW, Herzog ED, Hattar S, Blackshaw S
Cell Rep. 2014 May 8;7(3):609-22. doi: 10.1016/j.celrep.2014.03.060. Epub 2014 Apr 24.

14.10.2014 : Sandra
Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials.
Bikard D, Euler CW, Jiang W, Nussenzweig PM, Goldberg GW, Duportet X, Fischetti VA, Marraffini LA.
Nat Biotechnol. 2014 Oct 5. doi: 10.1038/nbt.3043. [Epub ahead of print]

07.10.2014 : Elyzana
Circadian rhythm reprogramming during lung inflammation.
Haspel JA, Chettimada S, Shaik RS, Chu JH, Raby BA, Cernadas M, Carey V, Process V, Hunninghake GM, Ifedigbo E, Lederer JA, Englert J1, Pelton A, Coronata A, Fredenburgh LE, Choi AM.
Nat Commun. 2014 Sep 11;5:4753. doi: 10.1038/ncomms5753.

30.09.2014 : no seminar




23.09.2014 : Bharath
A novel mechanism controlling resetting speed of the circadian clock to environmental stimuli.
Pilorz V, Cunningham PS, Jackson A, West AC, Wager TT, Loudon AS, Bechtold DA.
Curr Biol. 2014 Mar 31;24(7):766-73. doi: 10.1016/j.cub.2014.02.027. Epub 2014 Mar 20.

16.09.2014 : Sebastian
Transcriptional interference by antisense RNA is required for circadian clock function.
Xue Z, Ye Q, Anson SR, Yang J, Xiao G, Kowbel D, Glass NL, Crosthwaite SK, Liu Y.
Nature. 2014 Aug 17. doi: 10.1038/nature13671. [Epub ahead of print]

09.09.2014 : no seminar




02.09.2014 : AG Westermark
Partitioning Circadian Transcription by SIRT6 Leads to Segregated Control of Cellular Metabolism.
Masri S, Rigor P, Cervantes M, Ceglia N, Sebastian C, Xiao C, Roqueta-Rivera M, Deng C, Osborne TF, Mostoslavsky R, Baldi P, Sassone-Corsi P
Cell. 2014 Jul 31;158(3):659-72. doi: 10.1016/j.cell.2014.06.050.

26.08.2014 : Veronika
An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action.
Gibbs J, Ince L, Matthews L, Mei J, Bell T, Yang N, Saer B, Begley N, Poolman T, Pariollaud M, Farrow S, DeMayo F, Hussell T, Worthen GS, Ray D, Loudon A.
Nat Med. 2014 Aug;20(8):919-26. doi: 10.1038/nm.3599. Epub 2014 Jul 27.

19.08.2014 : Summer break




12.08.2014 : Summer break




05.08.2014 : Summer break




29.07.2014 : Summer break




22.07.2014 : Summer break




15.07.2014 : Summer break




08.07.2014 : Summer break




01.07.2014 : Summer break




24.06.2014 : SRBR Update




17.06.2014 : no seminar (SRBR)




10.06.2014 : Thomas
Insulin-FOXO3 signaling modulates circadian rhythms via regulation of clock transcription.
Chaves I1, van der Horst GT1, Schellevis R2, Nijman RM1, Koerkamp MG3, Holstege FC3, Smidt MP4, Hoekman MF5.
Curr Biol. 2014 Jun 2;24(11):1248-55. doi: 10.1016/j.cub.2014.04.018. Epub 2014 May 22.

03.06.2014 : Achim
Optical control of mammalian endogenous transcription and epigenetic states.
Konermann S1, Brigham MD, Trevino AE, Hsu PD, Heidenreich M, Cong L, Platt RJ, Scott DA, Church GM, Zhang F.
Nature. 2013 Aug 22;500(7463):472-6. doi: 10.1038/nature12466. Epub 2013 Aug 23.

27.05.2014 : no seminar




20.05.2014 : no seminar




13.05.2014 : Silke
A Positive Role for PERIOD in Mammalian Circadian Gene Expression.
Akashi M, Okamoto A, Tsuchiya Y, Todo T, Nishida E, Node K.
Cell Rep. 2014 Apr 30. pii: S2211-1247(14)00282-4. doi: 10.1016/j.celrep.2014.03.072. [Epub ahead of print]

06.05.2014 : Bert
Method seminar: CRISPR/CAS9 System



29.04.2014 : Ute
A novel protein, CHRONO, functions as a core component of the mammalian circadian clock.
Goriki A, Hatanaka F, Myung J, Kim JK, Yoritaka T, Tanoue S, Abe T, Kiyonari H, Fujimoto K, Kato Y, Todo T, Matsubara A, Forger D, Takumi T.
PLoS Biol. 2014 Apr 15;12(4):e1001839. doi: 10.1371/journal.pbio.1001839. eCollection 2014.

22.04.2014 : no seminar




15.04.2014 : guest lecture




08.04.2014 : Neta
Circadian clocks and feeding time regulate the oscillations and levels of hepatic triglycerides.
Adamovich Y1, Rousso-Noori L1, Zwighaft Z1, Neufeld-Cohen A1, Golik M1, Kraut-Cohen J1, Wang M2, Han X2, Asher G3.
Cell Metab. 2014 Feb 4;19(2):319-30. doi: 10.1016/j.cmet.2013.12.016.

01.04.2014 : Sandra
Identification and validation of cryptochrome inhibitors that modulate the molecular circadian clock.
Chun SK1, Jang J, Chung S, Yun H, Kim NJ, Jung JW, Son GH, Suh YG, Kim K.
http://www.ncbi.nlm.nih.gov/pubmed/?term=Identification+and+Validation+of+Cryptochrome

25.03.2014 : Elyzana
The circadian clock protein timeless regulates phagocytosis of bacteria in Drosophila.
Stone EF, Fulton BO, Ayres JS, Pham LN, Ziauddin J, Shirasu-Hiza MM.
PLoS Pathog. 2012 Jan;8(1):e1002445. doi: 10.1371/journal.ppat.1002445. Epub 2012 Jan 12.

18.03.2014 : Bharath
Paper of special interest



11.03.2014 : Veronika
Paper of special interest



04.03.2014 : AG Westermark
Circadian Control of Fatty Acid Elongation by SIRT1 Protein-mediated Deacetylation of Acetyl-coenzyme A Synthetase 1.
Sahar S1, Masubuchi S, Eckel-Mahan K, Vollmer S, Galla L, Ceglia N, Masri S, Barth TK, Grimaldi B, Oluyemi O, Astarita G, Hallows WC, Piomelli D, Imhof A, Baldi P, Denu JM, Sassone-Corsi P.
J Biol Chem. 2014 Feb 28;289(9):6091-7. doi: 10.1074/jbc.M113.537191. Epub 2014 Jan 14.

25.02.2014 : Sebastian
Mistimed sleep disrupts circadian regulation of the human transcriptome.
Archer SN1, Laing EE, Möller-Levet CS, van der Veen DR, Bucca G, Lazar AS, Santhi N, Slak A, Kabiljo R, von Schantz M, Smith CP, Dijk DJ.
Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):E682-91. doi: 10.1073/pnas.1316335111. Epub 2014 Jan 21.

18.02.2014 : Achim
Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock.
St John PC1, Hirota T, Kay SA, Doyle FJ 3rd.
Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):2040-5. doi: 10.1073/pnas.1323618111. Epub 2014 Jan 21.

11.02.2014 : Thomas
BMAL1-dependent regulation of the mTOR signaling pathway delays aging.
Khapre RV1, Kondratova AA, Patel S, Dubrovsky Y, Wrobel M, Antoch MP, Kondratov RV.
Aging (Albany NY). 2014 Jan;6(1):48-57.

04.02.2014 : Neta
CLOCK/BMAL1 regulates circadian change of mouse hepatic insulin sensitivity via SIRT1.
Zhou B, Zhang Y, Zhang F, Xia Y, Liu J, Huang R, Wang Y, Hu Y, Wu J, Dai C, Wang H, Tu Y, Peng X, Wang Y, Zhai Q.
Hepatology. 2014 Jan 18. doi: 10.1002/hep.26992. [Epub ahead of print]

28.01.2014 : no seminar




21.01.2014 : Silke
CLOCK:BMAL1 is a pioneer-like transcription factor.
Menet JS, Pescatore S, Rosbash M.
Genes Dev. 2014 Jan 1;28(1):8-13. doi: 10.1101/gad.228536.113.

14.01.2014 : Bert
Circadian clock-dependent and -independent rhythmic proteomes implement distinct diurnal functions in mouse liver.
Mauvoisin D, Wang J, Jouffe C, Martin E, Atger F, Waridel P, Quadroni M, Gachon F, Naef F.
Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):167-72. doi: 10.1073/pnas.1314066111. Epub 2013 Dec 16.

07.01.2014 : Ute
Reprogramming of the circadian clock by nutritional challenge.
Eckel-Mahan KL, Patel VR, de Mateo S, Orozco-Solis R, Ceglia NJ, Sahar S, Dilag-Penilla SA, Dyar KA, Baldi P, Sassone-Corsi P.
Cell. 2013 Dec 19;155(7):1464-78. doi: 10.1016/j.cell.2013.11.034.